Use this calculator to plan how many Pure Encapsulations Silymarin 250mg capsules and bottles you’ll need for a given time period, and see the estimated cost based on the current 120-count bottle price.
Milk Thistle (Silymarin) Dosage & Cost Calculator
Based on the labeled dose options for Pure Encapsulations Silymarin 250mg and the published 120-count bottle at $45.00.
Estimate only – based on the current listed price of the 120-count Pure Encapsulations Silymarin 250mg bottle. Actual Amazon price can change; check the live price before buying.
Why no height/weight input? Unlike per-kg supplements (creatine, protein), Milk Thistle (Silymarin) has no published bodyweight-adjusted dosing in the research behind it. This calculator doesn't fabricate a per-kg formula that doesn't exist in the literature.
Get Pure Encapsulations Silymarin 250mg on Amazon(paid link) As an Amazon Associate we earn from qualifying purchases.
This product’s label allows 1–4 capsules daily (250–1,000 mg), standardized to 80% silymarin.
It’s worth being direct about a well-designed negative trial here: a Phase II randomized, double-blind, placebo-controlled study in 78 patients with confirmed non-alcoholic steatohepatitis (NASH) tested silymarin at 420 mg or 700 mg three times daily (1,260–2,100 mg/day total) for 48 weeks and found no significant improvement in liver histology versus placebo, even at doses well above this product’s own label range [1]. We’re citing this study because it’s a rigorous, well-controlled trial, not because it supports a benefit — the evidence for silymarin’s liver effects is genuinely mixed across the research base.
As with the other calculators on our network, there’s no published bodyweight-adjusted dosing for milk thistle, so this tool plans by a fixed daily amount rather than your height or weight.